User profiles for Xiaoling Lu

Xiaoling Lu

Research scientist, RWTH Aachen University
Verified email at iwe1.rwth-aachen.de
Cited by 388

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

…, Y Guan, M Liu, Y Li, N Gao, L Wang, X Lu… - Nature …, 2013 - nature.com
To the Editor: CRISPR-Cas systems have been developed as an efficient gene editing
technology in cells and model organisms. Here we use a CRISPR-Cas system to induce genomic …

Label-free ultrasensitive memristive aptasensor

I Tzouvadaki, P Jolly, X Lu, S Ingebrandt… - Nano …, 2016 - ACS Publications
We present the very first worldwide ever-reported electrochemical biosensor based on a
memristive effect and DNA aptamers. This novel device is developed to propose a completely …

Radioprotective activity of betalains from red beets in mice exposed to gamma irradiation

X Lu, Y Wang, Z Zhang - European Journal of Pharmacology, 2009 - Elsevier
We investigated the radioprotective activity of betalains from red beets in mice irradiated by a
60 Co gamma (γ) ray (6.0 Gy, at a dose of 1.5 Gy min −1 ). Mice were randomly divided into …

Inhibition of ferroptosis protects House Ear Institute‐Organ of Corti 1 cells and cochlear hair cells from cisplatin‐induced ototoxicity

…, L Zhao, W Li, Z Zheng, D Tang, X Lu… - Journal of Cellular …, 2020 - Wiley Online Library
Ferroptosis is a recently recognized form of non‐apoptotic cell death caused by an iron‐dependent
accumulation of lipid hydroperoxides, which plays important roles in a wide spectrum …

Thermophysical properties of polycaprolactone/chitosan blend membranes

Y Wan, X Lu, S Dalai, J Zhang - Thermochimica Acta, 2009 - Elsevier
Biodegradable polycaprolactone/chiotosan blends with various proportions were prepared
using concentrated acetic acid solutions as solvents. The blends were further processed into …

Salt-inducible Kinase (SIK1) regulates HCC progression and WNT/β-catenin activation

C Qu, D He, X Lu, L Dong, Y Zhu, Q Zhao, X Jiang… - Journal of …, 2016 - Elsevier
Background & Aims In this study, we investigated the role of salt-inducible kinase 1 (SIK1)
and its possible mechanisms in human hepatocellular carcinoma (HCC). Methods …

[HTML][HTML] The enhanced antitumor-specific immune response with mannose-and CpG-ODN-coated liposomes delivering TRP2 peptide

…, J Zhao, X Yu, Z Hu, Z Tang, F Mo, X Yang, X Lu - Theranostics, 2018 - ncbi.nlm.nih.gov
Purpose: Dendritic cell (DC)-based cancer vaccines is a newly emerging and potent form of
immune therapy. As for any new technology, there are still considerable challenges that …

[HTML][HTML] Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea

…, X Lu, W Zhu, W Muhammad, L Zhang, L Lu… - Stem cell research & …, 2019 - Springer
Background Inner ear supporting cells (SCs) in the neonatal mouse cochlea are a potential
source for hair cell (HC) regeneration, but several studies have shown that the regeneration …

PEDOT: PSS organic electrochemical transistor arrays for extracellular electrophysiological sensing of cardiac cells

F Hempel, JKY Law, TC Nguyen, W Munief, X Lu… - Biosensors and …, 2017 - Elsevier
Electrophysiological biosensors embedded in planar devices represent a state of the art
approach to measure and evaluate the electrical activity of biological systems. This …

[HTML][HTML] Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor immunotherapy

…, S Xie, Z Ding, X Zhao, BD Hammock, X Lu - Signal transduction and …, 2021 - nature.com
Chimeric antigen receptor-based T-cell immunotherapy is a promising strategy for treatment
of hematological malignant tumors; however, its efficacy towards solid cancer remains …