Background Infection-related acute kidney injury (AKI) is an important preventable cause of
morbidity and mortality in the tropical region. The prevalence and outcome of kidney …

Reduced succinate dehydrogenase (SDH) activity resulting in adverse succinate accumulation
was previously considered relevant only in 0.05 to 0.5% of kidney cancers associated …

Background: Mutations in the SF3B1 splicing factor are commonly seen in myelodysplastic
syndromes (MDS) and acute myeloid leukemia (AML), yet the specific oncogenic pathways …

Background The most important concern with polymyxins (Colistin and Polymyxin B) use is
nephrotoxicity. There is no prospective data comparing nephrotoxicity of these two drugs, …

Second wave of COVID-19 pandemic in India came with unexpected quick speed and
intensity, creating an acute shortage of beds, ventilators, and oxygen at the peak of occurrence. …

Background Convalescent plasma (CP) is being used as a treatment option in hospitalized
patients with COVID-19. Till date, there is conflicting evidence on efficacy of CP in reducing …

Background Various immunomodulatory therapies have been explored to manage the
dysregulated immune response seen in severe COVID-19 infection. The objective of this study …

Dysregulation of the innate immune system and inflammatory-related pathways has been
implicated in hematopoietic defects in the bone marrow microenvironment and associated with …

Adult T-cell leukemia/lymphoma (ATLL) is an aggressive T-cell lymphoma associated with
the human T-cell lymphotropic virus type 1 virus endemic in regions including Japan, the …

Idiopathic pulmonary haemosiderosis (IPH) is characterized by a triad of recurrent episodes
of alveolar haemorrhage, haemoptysis and iron deficiency anaemia. The combination of IPH …