Stem cells are necessary for the maintenance of many adult tissues. Signals within the stem
cell microenvironment, or niche, regulate the self-renewal and differentiation capability of …

Adult stem cells are maintained in niches, specialized microenvironments that regulate their
self-renewal and differentiation. In the adult Drosophila testis stem cell niche, somatic hub …

Stem cells in tissues reside in and receive signals from local microenvironments called niches.
Understanding how multiple signals within niches integrate to control stem cell function is …

Endothelial cells display an extraordinary plasticity both during development and throughout
adult life. During early development, endothelial cells assume arterial, venous, or lymphatic …

Homeostasis in adult tissues depends on the precise regulation of stem cells and their
surrounding microenvironments, or niches. Here, we show that the cell cycle inhibitor and tumor …

Background Chronic pain is a prevalent and costly problem that often has occupational origins.
Home care workers (HCWs) are at high risk for work-related injuries, pain, and disability. …

Live imaging of adult tissue stem cell niches provides key insights into the dynamic behavior
of stem cells, their differentiating progeny, and their neighboring support cells, but few …

COVID-19 has had a substantial impact on transit workers’ lives, especially among public-facing
vehicle operators. The current project examined relationships between workers’ …

Variation in reproductive success has long been thought to be mediated in part by genes
encoding seminal proteins. Here we explore the effect on male reproductive phenotypes of X-…

Cutaneous wounds are common afflictions that follow a stereotypical healing process involving
hemostasis, inflammation, proliferation, and remodeling phases. In the elderly and those …