RT Journal Article SR Electronic T1 Effects of Animation and Rotoscoping In Direct-to-Consumer Rx TV Advertising JF Journal of Advertising Research JO J Advert Res FD WARC SP JAR-2021-016 DO 10.2501/JAR-2021-016 A1 AMIE C. O’DONOGHUE A1 KEVIN R. BETTS A1 SARAH PARVANTA A1 MIHAELA JOHNSON A1 BRIDGET KELLY A1 NICOLE MACK YR 2021 UL http://www.journalofadvertisingresearch.com/content/early/2021/10/27/JAR-2021-016.abstract AB This study experimentally tested the effects of animation versus rotoscoping versus live action in direct-to-consumer television advertising on outcomes, including risk and benefit perceptions and attitudes toward the drug. The authors used an online panel to recruit participants with chronic dry eye (n = 504) and psoriasis (n = 490). The study found no effects of animation or rotoscoping on perceptions of drug risk or benefit, comprehension, or behavioral intentions. Animated advertisements, however, resulted in more negative attitudes than live-action or rotoscoped advertisements. Future research should explore whether animated advertisements are recalled better over time or have any lagged effects on perceptions.