The majority of large companies have in place consumer segmentations that identify “discrete”
groups against which to target different business activities (eg, new-product development)…

KL-ONE is a system for representing knowledge in Artificial Intelligence programs. It has been
developed and refined over a long period and has been used in both basic research and …

Objective: Prostate-specific membrane antigen (PSMA) is a cell-surface protein widely
expressed on most prostate cancer cells that has rapidly emerging clinical utility in the realm of …

Within this chapter we discuss future changes in customer needs. We start this exploration
of the future with a brief reflection of the past, and discuss how meeting existing customer …

Background Alteration of the PI3K/AKT/mTOR pathway is a common genomic abnormality
detected in triple-negative breast cancer (TNBC). Everolimus acts synergistically with eribulin …

An 80-year-old male patient presented with a 3-month history of hematuria, urinary incontinence,
and reported penile skin darkening. Physical exam revealed a fungating penile mass …

Motivation: A major goal of biomedical research is to identify molecular features associated
with a biological or clinical class of interest. Differential expression analysis has long been …

Purpose: Emerging data suggest immune checkpoint inhibitors have reduced efficacy in
heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are …

Within this paper the authors argue that traditional forms of segmentation may be limited by
the failure of the identified segments to differ significantly on important “profiling” variables. A …

… Their solution to the serialization problem (which they call the synchronization problem) is,
for each rule r in a given set of rules R, identify those rules that r cannot coexecute with. Once …