During the past decades, anticancer immunotherapy has evolved from a promising therapeutic
option to a robust clinical reality. Many immunotherapeutic regimens are now approved …

Much recent research on c-Myc has focused on how it drives apoptosis. c-Myc is widely known
as a crucial regulator of cell proliferation in normal and neoplastic cells, but until relatively …

… The suppression of proliferation was associated with G 1 /S-phase arrest rather than a
cytotoxic mechanism. Natural tryptophan catabolites as well as 3,4-DAA reduced the release of IL-…

… Prendergast is co-founder, president and chief scientific officer and significant stockholder
in OncoRx, Inc., a start-up biotechnology company that aims to develop the therapeutic …

We have identified a novel protein, BAP1, which binds to the RING finger domain of the
Breast/Ovarian Cancer Susceptibility Gene product, BRCA1. BAP1 is a nuclear-localized, …

The three-dimensional structure of the basic/helix–loop–helix/leucine zipper domain of the
transcription factor Max complexed with DNA has been determined by X-ray crystallography …

This paper extends work on the influence of awareness, purchase and dream values of
luxury brands on two counts. First, it introduces a measure on consumers' ‘dislike’ for certain …

… Kolb, in Advances its Electrochemistry and Electrochemical Etngitneerin~g, H. Gerisher and
C. … Prendergast for stimulating discussion; R. Metz for a gift of HeLa nuclear extract; and B. …

Disease tolerance is the ability of the host to reduce the effect of infection on host fitness.
Analysis of disease tolerance pathways could provide new approaches for treating infections …

Indoleamine 2,3-dioxygenase (IDO) is an immunosuppressive enzyme that contributes to
tolerance in a number of biological settings. In cancer, IDO activity may help promote acquired …