User profiles for Tsai Chen

Tsai-Wen Chen (陳摘文)

- Verified email at nycu.edu.tw - Cited by 12870

Chen-Tsang (Simon) Tsai

- Verified email at mail.tut.edu.tw - Cited by 3928

Ultrasensitive fluorescent proteins for imaging neuronal activity

TW Chen, TJ Wardill, Y Sun, SR Pulver, SL Renninger… - Nature, 2013 - nature.com
Fluorescent calcium sensors are widely used to image neural activity. Using structure-based
mutagenesis and neuron-based screening, we developed a family of ultrasensitive protein …

Optimization of a GCaMP calcium indicator for neural activity imaging

J Akerboom, TW Chen, TJ Wardill, L Tian… - Journal of …, 2012 - Soc Neuroscience
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience.
Recent efforts in protein engineering have significantly increased the performance of …

[HTML][HTML] Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations

…, CL Tsai, JCH Yang, YM Chen… - … England Journal of …, 2020 - Mass Medical Soc
Background A splice-site mutation that results in a loss of transcription of exon 14 in the
oncogenic driver MET occurs in 3 to 4% of patients with non–small-cell lung cancer (NSCLC). …

An optimized fluorescent probe for visualizing glutamate neurotransmission

…, J Akerboom, A Gordus, SL Renninger, TW Chen… - Nature …, 2013 - nature.com
We describe an intensity-based glutamate-sensing fluorescent reporter (iGluSnFR) with
signal-to-noise ratio and kinetics appropriate for in vivo imaging. We engineered iGluSnFR in …

Government websites for promoting East Asian culinary tourism: A cross-national analysis

JS Horng, CTS Tsai - Tourism management, 2010 - Elsevier
The content of government tourism websites is very important for promoting a tourist destination's
exciting cuisine and food culture. These websites help to shape a country's, region's or …

[HTML][HTML] Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

…, TJ Wardill, E Fischer, C Schüler, TW Chen… - Frontiers in molecular …, 2013 - frontiersin.org
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience.
Here we describe red, single-wavelength GECIs, “RCaMPs,” engineered from circular …

In vitro evaluation of cytotoxicity of a naturally occurring cross-linking reagent for biological tissue fixation

…, RN Huang, LLH Huang, CC Tsai - Journal of Biomaterials …, 1999 - Taylor & Francis
A recognized drawback of the currently available chemical cross-linking reagents used to fix
bioprostheses is the potential toxic effects a recipient may be exposed to from the fixed …

Memorable tourist experiences and place attachment when consuming local food

CT Tsai - International Journal of Tourism Research, 2016 - Wiley Online Library
The purpose of the study was to model the memorable travel experiences, place attachment
and behavioral intentions for consuming local food. Data were collected by self‐…

[HTML][HTML] Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging In Vivo

H Dana, TW Chen, A Hu, BC Shields, C Guo… - PloS one, 2014 - journals.plos.org
Genetically-encoded calcium indicators (GECIs) facilitate imaging activity of genetically
defined neuronal populations in vivo. The high intracellular GECI concentrations required for in …

Experiential value in branding food tourism

CTS Tsai, YC Wang - Journal of Destination Marketing & Management, 2017 - Elsevier
Although food tourism has been characterized as an emerging industry, studies of branding
in food tourism are limited. This work applies a novel, value-driven approach to evaluate …