Early studies of response to print advertising showed a pattern of simple-power functions to
describe inquiry and memorial response. Contemporary psychology has established a world …

Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a target
molecule. We sought to determine whether aptamers have potential for in vivo delivery of …

Organization in biological membranes spans many orders of magnitude in length scale, but
limited resolution in far-field light microscopy has impeded distinction between numerous …

Background Precision medicine approaches that target patients on the basis of disease
subtype have transformed treatment approaches to cancer, asthma, and other heterogeneous …

Tenascin-C (TN-C) is an extracellular matrix protein that is overexpressed during tissue
remodeling processes, including tumor growth. To identify an aptamer for testing as a tumor-…

Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) is a putative fast-acting
antidepressant candidate. Although inhibition of NMDA-type glutamate receptors (NMDARs) …

The existence of extracellular DNA in human plasma, also known as cell‐free DNA (cf DNA ),
was first described in the 1940s. In recent years, there has been a resurgence of interest in …

It has long been hypothesized that conditioning mechanisms play major roles in addiction.
Specifically, the associations between rewarding properties of drugs of abuse and the drug …

Nicotine has been demonstrated to enhance learning processes. The present experiments
extend these results to examine the effects of nicotine on acquisition and consolidation of …

While the health risks associated with adult cigarette smoking have been well described,
effects of nicotine exposure during periods of developmental vulnerability are often overlooked. …