Advertising researchers do not understand fully the impact different advertisement placement
and delivery vehicles have on the mobile user's experience. To better grasp the mobile …

DNA methylation (DNAm)-based biomarkers of aging have been developed for many tissues
and organs. However, these biomarkers have sub-optimal accuracy in fibroblasts and other …

A confounding aspect of biological ageing is the nature and role of senescent cells. It is
unclear whether the three major types of cellular senescence, namely replicative senescence, …

The paramount role of senescent cells in ageing has prompted suggestions that re-expression
of telomerase may prevent ageing; a proposition that is predicated on the assumption that …

The advent of epigenetic clocks has prompted questions about the place of epigenetic
ageing within the current understanding of ageing biology. It was hitherto unclear whether …

The power of mathematical analyses that are brought to bear on large DNA methylation
data sets is uncovering previously unknown aspects of aging. By far, the most significant …

The definition of epigenetics has changed as a result of greater understanding of the numerous
ways by which gene expression is controlled in the cell. As such, it is necessary to clarify …

Purpose: Surgery is a major risk factor for chronic opioid use among patients who had not
recently been prescribed opioids. This study identifies the rate of, and risk factors for, …

THIS IS THE FIRST OF 2 ARTICLES EVALUATING cardiac events in patients undergoing
noncardiac surgery. In this article, we review the magnitude of the problem, the …

Partial cDNA and genomic clones of rat stem cell factor (SCF) have been isolated. Using
probes based on the rat sequence, partial and full-length cDNA and genomic clones of human …