Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover
new antibiotics. To address this challenge, we trained a deep neural network capable of …

… James C. Collins is a management educator and writer based in Boulder, Colorado, where
he operates a management learning laboratory for conducting research and working with …

Machine learning, a collection of data-analytical techniques aimed at building predictive
models from multi-dimensional datasets, is becoming integral to modern biological research. By …

Antibiotic drug–target interactions, and their respective direct effects, are generally well
characterized. By contrast, the bacterial responses to antibiotic drug treatments that contribute to …

It has been proposed 1 that gene-regulatory circuits with virtually any desired property can
be constructed from networks of simple regulatory elements. These properties, which include …

Clinical application of induced pluripotent stem cells (iPSCs) is limited by the low efficiency
of iPSC derivation and the fact that most protocols modify the genome to effect cellular …

This book is dedicated to Dr. Benjamin William Remondi for many reasons. The project of
writing a Global Positioning System (GPS) book was con ceived in April 1988 at a GPS …

This review explores questions of power, epistemology, cultural form, and historical process,
as they are raised by and developed in studies of literacy. It begins by reviewing arguments …

Antibiotic mode-of-action classification is based upon drug-target interaction and whether
the resultant inhibition of cellular function is lethal to bacteria. Here we show that the three …

Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen
detection, genotyping, and disease monitoring. The RNA-guided, RNA-targeting clustered …