User profiles for J. Kleinnijenhuis
Jan KleinnijenhuisProfessor of Communication Science, Vrije Universiteit Amsterdam Verified email at vu.nl Cited by 5341 |
[HTML][HTML] Innate Immune Recognition of Mycobacterium tuberculosis
J Kleinnijenhuis, M Oosting, LAB Joosten… - Journal of Immunology …, 2011 - hindawi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem,
with 10 million new cases diagnosed each year. Innate immunity plays an important role in …
with 10 million new cases diagnosed each year. Innate immunity plays an important role in …
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
J Kleinnijenhuis, J Quintin, F Preijers… - Proceedings of the …, 2012 - National Acad Sciences
Adaptive features of innate immunity, recently described as “trained immunity,” have been
documented in plants, invertebrate animals, and mice, but not yet in humans. Here we show …
documented in plants, invertebrate animals, and mice, but not yet in humans. Here we show …
Trained immunity: consequences for the heterologous effects of BCG vaccination
J Kleinnijenhuis, R Van Crevel… - Transactions of the …, 2015 - academic.oup.com
A growing body of evidence from epidemiologic and immunologic studies have shown that
in addition to target disease-specific effects, vaccines have heterologous effects towards …
in addition to target disease-specific effects, vaccines have heterologous effects towards …
The role of autophagy in host defence against Mycobacterium tuberculosis infection
M Songane, J Kleinnijenhuis, MG Netea, R van Crevel - Tuberculosis, 2012 - Elsevier
Autophagy is a vital homeostatic process triggered by starvation and other cellular stresses,
in which cytoplasmatic cargo is targeted for degradation in specialized structures termed …
in which cytoplasmatic cargo is targeted for degradation in specialized structures termed …
Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity
J Kleinnijenhuis, J Quintin, F Preijers, CS Benn… - Journal of innate …, 2014 - karger.com
We have recently shown that BCG (Bacillus Calmette-Guérin) vaccination in healthy
volunteers induces epigenetic reprogramming of monocytes, leading to increased cytokine …
volunteers induces epigenetic reprogramming of monocytes, leading to increased cytokine …
[BOOK][B] Doing research in political science: An introduction to comparative methods and statistics
This is an immensely helpful book for students starting their own research... an excellent
introduction to the comparative method giving an authoritative overview over the research …
introduction to the comparative method giving an authoritative overview over the research …
[PDF][PDF] Immunometabolic pathways in BCG-induced trained immunity
…, C Palma, F Rodrigues, R Silvestre, J Kleinnijenhuis… - Cell reports, 2016 - cell.com
The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated
infections are thought to be mediated by long-term metabolic changes and chromatin …
infections are thought to be mediated by long-term metabolic changes and chromatin …
BCG-induced trained immunity in NK cells: role for non-specific protection to infection
J Kleinnijenhuis, J Quintin, F Preijers, LAB Joosten… - Clinical …, 2014 - Elsevier
Adaptive features of innate immunity, also termed ‘trained immunity’, have recently been
shown to characterize monocytes of BCG vaccinated healthy volunteers. Trained immunity …
shown to characterize monocytes of BCG vaccinated healthy volunteers. Trained immunity …
News selection criteria in the digital age: Professional norms versus online audience metrics
On newspaper websites, journalists can observe the preferences of the audience in
unprecedented detail and for low costs, based on the audience clicks (ie page views) for specific …
unprecedented detail and for low costs, based on the audience clicks (ie page views) for specific …
Strategic framing in the BP crisis: A semantic network analysis of associative frames
This paper contributes to the analysis of the interplay of public relations and news in crisis
situations, and the conceptualization of strategic framing by introducing the idea of associative …
situations, and the conceptualization of strategic framing by introducing the idea of associative …