Simple Summary This review article comprehensively discussed the evolution of the SARS-CoV-2
virus since its initial outbreak in 2019. Specifically, we have provided insights into the …

Ceramide and sphingosine are important interconvertible sphingolipid metabolites which
govern various signaling pathways related to different aspects of cell survival and senescence. …

Hallmark features of Alzheimer’s disease (AD) include elevated accumulation of aggregated
Aβ40 and Aβ42 peptides, hyperphosphorylated Tau (p-Tau), and neuroinflammation. …

Aging is associated with increased prevalence and severity of pathogenic outcomes of
periodontal disease, including soft tissue degeneration and bone loss around the teeth. Although …

… The signal intensity of Western blots was quantified using Image J. … The signal quantification
was carried out using Image J. ANOVA with Tukey’s post-hoc test was used to evaluate the …

Brands see major live events as opportunities to connect with consumers and to build brand
equity and sales. In this article, we describe how the classical MCA® methodology was …

Although periprosthetic osteolysis induced by wear debris particles is significantly elevated
in senior (65+ years old) patients, most of the published pre-clinical studies were performed …

The SARS-CoV-2 virus causes elevated production of senescence-associated secretory
phenotype (SASP) markers by macrophages. SARS-CoV-2 enters macrophages through its …

Emerging studies indicate that intracellular eukaryotic ceramide species directly activate
cathepsin B (CatB), a lysosomal‐cysteine‐protease, in the cytoplasm of osteoclast precursors (…

The leucine-rich repeat-containing protein 25 (LRRC25) is relatively a novel protein with no
information on its role in neuronal or brain function. A recent study suggested LRRC25 is a …