[HTML][HTML] Mortality and risk factors associated with pulmonary embolism in coronavirus disease 2019 patients: a systematic review and meta-analysis

CA Gómez, CK Sun, IT Tsai, YP Chang, MC Lin… - Scientific reports, 2021 - nature.com
To determine, in patients with coronavirus disease 2019 (COVID-19) infection, the
associations of pulmonary embolism (PE) with mortality and risk factors for PE as well as the …

[HTML][HTML] “Diabetic striatopathy”: clinical presentations, controversy, pathogenesis, treatments, and outcomes

…, CK Sun, CW Hsu, YC Tai, CY Liang, IT Tsai - Scientific reports, 2020 - nature.com
Diabetic striatopathy (DS) is a rare medical condition with ambiguous nomenclature. We
searched PubMed database from 1992 to 2018 for articles describing hyperglycemia …

[HTML][HTML] Alcohol-related liver disease: basic mechanisms and clinical perspectives

SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis, …

[HTML][HTML] FABP1 and FABP2 as markers of diabetic nephropathy

IT Tsai, CC Wu, WC Hung, TL Lee… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
Background: Diabetes mellitus is the leading cause of diabetic nephropathy and a major
public health issue worldwide. Approximately 20-30% of patients with type 2 diabetes mellitus (…

[HTML][HTML] The burden of major adverse cardiac events in patients with coronary artery disease

IT Tsai, CP Wang, YC Lu, WC Hung, CC Wu… - BMC cardiovascular …, 2017 - Springer
Background Patients with a history of cardiovascular disease are at high risk of developing
secondary major adverse cardiac events (MACE). This study aimed to identify independent …

Circulating secreted frizzled‐related protein 5 (Sfrp5) and wingless‐type MMTV integration site family member 5a (Wnt5a) levels in patients with type 2 diabetes …

…, WC Hung, LF Lu, FM Chung, IT Tsai… - Diabetes/metabolism …, 2013 - Wiley Online Library
Background Secreted frizzled‐related protein 5 (Sfrp5), an endogenous inhibitor of wingless‐type
MMTV integration site family (Wnt) signalling, is an anti‐inflammatory adipokine …

[HTML][HTML] Increased levels of total P-Cresylsulphate and indoxyl sulphate are associated with coronary artery disease in patients with diabetic nephropathy

…, TH Yu, WC Hung, FM Chung, IT Tsai… - The review of diabetic …, 2010 - ncbi.nlm.nih.gov
BACKGROUND: Indoxyl sulphate (IS) and p-cresylsulphate (PCS) are uremic toxins with
similar protein-binding, dialytic clearance, and proinflammatory features. Few studies have …

[HTML][HTML] Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

…, CC Chang, CP Wang, WC Hung, IT Tsai… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Background: Fatty acid-binding protein 1 (FABP1)(also known as liver-type fatty acid-binding
protein or LFABP) is a protein that is mainly expressed in the liver, and is associated with …

Levels of indoxyl sulfate are associated with severity of coronary atherosclerosis

…, LF Lu, FM Chung, YJ Lee, IT Tsai - Clinical and …, 2013 - utpjournals.press
Purpose Indoxyl sulfate (IS) is linked to endothelial damage, NF-αB activation and induced
development of atherosclerosis. The purpose of this study was to investigate the relationship …

Andrographolide inhibits ICAM-1 expression and NF-κB activation in TNF-α-treated EA. hy926 cells

…, CK Lii, IT Tsai, CC Li, KL Liu, CW Tsai… - Journal of agricultural …, 2011 - ACS Publications
Several lines of evidence indicate that inflammation and endothelial cell dysfunction are
important initiating events in atherosclerosis. Tumor necrosis factor-α (TNF-α), a pro-…